All controlled substance prescribers in California are required to register to access the state prescription drug monitoring program known as CURES (Controlled Substance Utilization Review and Evaluation System). Beginning April 11, 2022, the site will no longer be accessible to those using the Internet Explorer (IE) browser. Also, after that date, prescribers who utilize delegates must enter into new delegate agreements for them to have continued access to CURES. A sample CURES delegate agreement can be downloaded below. A copy of the signed delegate agreement must be retained by both parties for a period of five years from the expiration date.